Angelo Antonini Selected Research

Levodopa (L Dopa)

9/2022	Opicapone as an Add-on to Levodopa in Patients with Parkinson's Disease Without Motor Fluctuations: Rationale and Design of the Phase III, Double-Blind, Randomised, Placebo-Controlled EPSILON Trial.
3/2022	Opicapone versus placebo in the treatment of Parkinson's disease patients with end-of-dose motor fluctuation-associated pain: rationale and design of the randomised, double-blind OCEAN (OpiCapone Effect on motor fluctuations and pAiN) trial.
1/2022	Does the 5-2-1 criteria identify patients with advanced Parkinson's disease? Real-world screening accuracy and burden of 5-2-1-positive patients in 7 countries.
8/2021	Personalised Advanced Therapies in Parkinson's Disease: The Role of Non-Motor Symptoms Profile.
6/2021	Correction to: The TANDEM investigation: efficacy and tolerability of levodopa-carbidopa intestinal gel in (LCIG) advanced Parkinson's disease patients.
1/2021	The Long-Term Impact of Levodopa/Carbidopa Intestinal Gel on 'Off'-time in Patients with Advanced Parkinson's Disease: A Systematic Review.
1/2021	The Added Benefit of Opicapone When Used Early in Parkinson's Disease Patients With Levodopa-Induced Motor Fluctuations: A Post-hoc Analysis of BIPARK-I and -II.
10/2020	Application of the '5-2-1' screening criteria in advanced Parkinson's disease: interim analysis of DUOGLOBE.
10/2020	Long-term effectiveness of levodopa-carbidopa intestinal gel on motor and non-motor symptoms in advanced Parkinson's disease: results of the Italian GLORIA patient population.
1/2020	Safety of Levodopa-Carbidopa Intestinal Gel Treatment in Patients with Advanced Parkinson's Disease Receiving ≥2000 mg Daily Dose of Levodopa.

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Angelo Antonini Research Topics

Disease

169	Parkinson Disease (Parkinson's Disease) 09/2022 - 11/2003
38	Dyskinesias (Dyskinesia) 01/2022 - 05/2006
17	Parkinsonian Disorders (Parkinsonism) 05/2021 - 11/2002
13	Tremor (Tremors) 01/2022 - 07/2007
12	Cognitive Dysfunction 09/2022 - 05/2009
12	Dementia (Dementias) 01/2021 - 06/2007
9	Movement Disorders (Movement Disorder) 02/2022 - 12/2007
8	Pain (Aches) 03/2022 - 09/2008
8	Disruptive, Impulse Control, and Conduct Disorders (Kleptomania) 11/2017 - 09/2007
7	Gambling (Pathological Gambling) 06/2011 - 02/2008
6	Disease Progression 12/2019 - 12/2008
5	Multiple System Atrophy 08/2014 - 11/2002
4	Deglutition Disorders (Dysphagia) 03/2022 - 01/2016
4	Fatigue 02/2022 - 01/2011
4	Essential Tremor (Essential Tremors) 04/2010 - 07/2007
3	COVID-19 08/2021 - 05/2020
3	Atrophy 12/2020 - 06/2004
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 01/2016
3	Sleep Wake Disorders 01/2020 - 01/2010
3	Polyneuropathies (Polyneuropathy) 01/2019 - 05/2013
3	Hallucinations (Hallucination) 12/2018 - 06/2007
3	Orthostatic Hypotension (Postural Hypotension) 01/2017 - 01/2013
3	Corticobasal Degeneration 05/2013 - 01/2010
3	Heart Valve Diseases (Valvular Heart Disease) 10/2011 - 01/2007
2	Inflammation (Inflammations) 01/2020 - 01/2017
2	Psychotic Disorders (Schizoaffective Disorder) 01/2019 - 09/2017
2	Edema (Dropsy) 02/2018 - 11/2016
2	Infections 12/2017 - 01/2017
2	Progressive Supranuclear Palsy (Steele Richardson Olszewski Syndrome) 07/2017 - 01/2010
2	Hemorrhage 01/2017 - 04/2010
2	Anhedonia 06/2015 - 07/2013
2	Hyperhomocysteinemia 01/2014 - 05/2009
2	Compulsive Sexual Behavior Disorder 02/2011 - 02/2008
1	Neurobehavioral Manifestations 10/2021
1	Seizures (Absence Seizure) 01/2021
1	Major Depressive Disorder (Major Depressive Disorders) 01/2021
1	Amyloid Plaque 01/2021
1	Malnutrition (Nutritional Deficiencies) 01/2021
1	Death (Near-Death Experience) 01/2021
1	Mitochondrial Diseases (Mitochondrial Disease) 01/2021
1	Amyloidosis 01/2021
1	Sleep Initiation and Maintenance Disorders (Insomnia) 11/2020
1	Respiratory Sounds (Crackle) 10/2019

Drug/Important Bio-Agent (IBA)

70	Levodopa (L Dopa)FDA LinkGeneric 09/2022 - 11/2003
24	Carbidopa (Lodosyn)FDA LinkGeneric 08/2021 - 07/2009
22	Pharmaceutical PreparationsIBA 01/2020 - 07/2007
21	Dopamine Agonists (Dopamine Agonist)IBA 11/2017 - 05/2006
17	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 10/2021 - 03/2006
17	Dopamine (Intropin)FDA LinkGeneric 05/2021 - 07/2007
15	Apomorphine FDA Link 08/2021 - 11/2003
10	Biomarkers (Surrogate Marker)IBA 12/2019 - 12/2008
8	2- carbomethoxy- 8- (3- fluoropropyl)- 3- (4- iodophenyl)tropaneIBA 01/2020 - 09/2007
6	Dopamine Receptors (Dopamine Receptor)IBA 01/2021 - 03/2004
6	Pramipexole (Mirapex)FDA LinkGeneric 06/2015 - 09/2004
5	Antipsychotic Agents (Antipsychotics)IBA 11/2020 - 02/2006
4	SynucleinsIBA 01/2021 - 01/2012
4	Cabergoline FDA LinkGeneric 06/2015 - 01/2007
3	opicaponeIBA 09/2022 - 01/2021
3	ioflupaneIBA 05/2021 - 08/2006
3	Amyloid (Amyloid Fibrils)IBA 01/2021 - 01/2018
3	hydroxide ionIBA 01/2017 - 01/2013
3	rotigotine FDA Link 12/2013 - 01/2010
3	Pergolide (Permax)FDA Link 12/2011 - 01/2007
3	Phosphotransferases (Kinase)IBA 01/2007 - 03/2006
3	Leucine (L-Leucine)FDA Link 01/2007 - 03/2006
2	mesoglycanIBA 03/2022 - 11/2021
2	levodopa drug combination carbidopa (Nakom)FDA LinkGeneric 01/2021 - 04/2016
2	SuspensionsIBA 01/2021 - 04/2016
2	Proteins (Proteins, Gene)FDA Link 12/2019 - 11/2018
2	Amantadine (Aman)FDA LinkGeneric 12/2019 - 02/2015
2	LigandsIBA 07/2017 - 07/2008
2	salicylhydroxamic acid (SHAM)IBA 05/2016 - 11/2015
2	HomocysteineIBA 01/2014 - 05/2009
2	Tolcapone (Tasmar)FDA Link 12/2008 - 02/2008
2	Sertraline (Zoloft)FDA LinkGeneric 08/2006 - 05/2006
1	Dopa DecarboxylaseIBA 03/2022
1	Glutamic Acid (Glutamate)FDA Link 02/2022
1	safinamideIBA 02/2022
1	Amyloid beta-PeptidesIBA 01/2021
1	AldehydesIBA 01/2021
1	flutemetamolIBA 01/2021
1	BenzodiazepinesIBA 01/2021
1	Pemetrexed (MTA)FDA Link 12/2020
1	Angiotensin-Converting Enzyme 2IBA 01/2020

Therapy/Procedure

51	Therapeutics 03/2022 - 11/2003
39	Deep Brain Stimulation 04/2022 - 11/2003
13	Activities of Daily Living (ADL) 09/2022 - 03/2010
5	Subcutaneous Infusions 08/2021 - 11/2003
4	Palliative Care (Palliative Therapy) 01/2022 - 01/2021
4	Gastrostomy 01/2021 - 06/2007
3	Denervation 10/2021 - 01/2010
3	Operative Surgical Procedures 05/2014 - 01/2007
2	Electrocoagulation (Electrocautery) 01/2022 - 01/2022
2	Wearable Electronic Devices 01/2020 - 01/2018
2	Cognitive Training 11/2017 - 05/2016
2	Transcranial Direct Current Stimulation 05/2016 - 01/2016
2	Secondary Prevention 01/2012 - 11/2010
1	Precision Medicine 12/2019
1	Tracheostomy 10/2019
1	Continuous Positive Airway Pressure 10/2019